Transperineal Prostate Biopsy

Key Points

  • Ultrasound-guided transperineal biopsy of your prostate is done to check for prostate cancer.

  • Currently, there is no more reliable way than biopsies for checking your prostate 

  • Prostate cancer is very common: 20% of Australian men will get prostate cancer by the age of 85.

  • Many of the newly diagnosed prostate cancers are not life-threatening; they may require no active treatment and can be carefully monitored.

What does this procedure involve?

  • You will often have an MRI scan of th prostate first. The prostate MRI helps to determine if you need a prostate biopsy. It also helps to identify any suspicious lesions or areas that we can target during the biopsy.

  • An ultrasound probe is inserted into your rectum (back passage) to scan your prostate.

  • Using this ultrasound as a guide, biopsies are taken from your prostate through your perineum (the skin between your scrotum and rectum).

  • The procedure is performed under intravenous sedation or general anaesthesia in theatre. 

What are the alternatives?

  • Observation with repeat PSA blood tests and possibly repeat MRI scans.

  • Transrectal prostate biopsies can be performed but are not recommended by the guidelines due to higher risk of severe infection or urosepsis.

What happens on the day of the procedure?

  • Dr Ashrafi will meet with you to confirm your consent and perform a team time-out prior to the procedure.

  • The anaesthetist will also see you to discuss the type of anaesthetic used and any pain relief required after the procedure.

How is the procedure performed?

  • Before the procedure, we will give you an antibiotic injection.

  • We will position your legs in special supports (stirrups) that allow the surgeon to access the skin behind your scrotum.

  • We may use tape to move your scrotum out of the way.

  • We will use an antiseptic solution to clean your perineum.

  • An ultrasound probe is inserted into the back passage (rectum).

  • We may use a special grid so that all areas of the prostate can be included in the biopsies.

  • The biopsy needles are guided into position using the ultrasound scanner.

  • Biopsies are taken from different zones of the prostate with extra samples from any suspicious areas seen on MRI.

  • The number of biopsies taken depends on your PSA level, the MRI report, and the prostate volume.

  • Dr Ashrafi may inject a local anaesthetic during the case to help with post-operative pain.

  • We will apply a dressing to your perineum after the biopsy

  • After the procedure, you will go to Recovery and then to the Daystay Ward.

  • You should expect to go home after a few hours when you are 1) comfortable and 2) able to void.

  • You may need a post-operative catheter into your bladder if you cannot void after the procedure; in this instance, you may be admitted and the catheter is usually removed the next day.

What are the risks and after-effects of the procedure?

Some of the possible after-effects are listed below. The impact of these after-effects can vary a lot from patient to patient. Please ask your surgeon’s advice about the risks and their impact on you as an individual.

  • Blood in the urine for up to 2 weeks (almost all patients).

  • Blood in your semen which can last up to six weeks; this poses no risk to you or your sexual partner (almost all patients).

  • Bruising in your scrotum and perineum (almost all patients).

  • Temporary issues with erections after the biopsy (5%).

  • Urinary retention or Inability to pass urine (5%); you may need a catheter and admission to hospital.

  • Urinary infection (1%).

  • False-negative results or failure to detect cancer in your prostate (2-10%).

  • Needing a repeat biopsy if the biopsies are inconclusive (2%).

Please contact us on 8119 0961 if you have any questions.

You can read more reliable, up-to-date and factual health information about a wide range of urological conditions here.

“Each patient is unique. You can be assured that we will partner with you to ensure your urological care is customised to your specific needs.”